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Regulation of Synaptic Structure by Ubiquitin C-Terminal Hydrolase L1

Ubiquitin C-terminal hydrolase L1 (UCH-L1) is a deubiquitinating enzyme that is selectively and abundantly expressed in the brain, and its activity is required for normal synaptic function. Here, we show that UCH-L1 functions in maintaining normal synaptic structure in hippocampal neurons. We found...

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Detalhes bibliográficos
Main Authors: Cartier, Anna E., Djakovic, Stevan N., Salehi, Afshin, Wilson, Scott M., Masliah, Eliezer, Patrick, Gentry N.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748938/
https://ncbi.nlm.nih.gov/pubmed/19535597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1817-09.2009
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