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An Essential Postsynaptic Role for the Ubiquitin Proteasome System in Slow Homeostatic Synaptic Plasticity in Cultured Hippocampal Neurons

Chronic increases or decreases in neuronal activity initiate compensatory changes in synaptic strength that emerge slowly over a 12–24 hr period, but the mechanisms underlying this slow homeostatic response remain poorly understood. Here, we show an essential role for the ubiquitin proteasome system...

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Detalhes bibliográficos
Main Authors: Jakawich, Sonya K., Neely, Ryan M., Djakovic, Stevan N., Patrick, Gentry N., Sutton, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024716/
https://ncbi.nlm.nih.gov/pubmed/20888892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2010.09.061
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