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Ubiquitin C-terminal hydrolase L1 (UCH-L1): structure, distribution and roles in brain function and dysfunction

Ubiquitin C-terminal hydrolase L1 (UCH-L1) is an extremely abundant protein in the brain where, remarkably, it is estimated to make up 1–5% of total neuronal protein. Although it comprises only 223 amino acids it has one of the most complicated 3D knotted structures yet discovered. Beyond its expres...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Bishop, Paul, Rocca, Dan, Henley, Jeremy M.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980807/
https://ncbi.nlm.nih.gov/pubmed/27515257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20160082
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