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A human DNA-binding protein is methylation-specific and sequence-specific.

A nuclear protein isolated from human placenta, methylated DNA-binding protein (MDBP), binds selectively to DNA enriched in 5-methylcytosine. We now demonstrate that MDBP is a sequence-specific, as well as methylation-specific, DNA-binding protein. From ten restriction fragments of pBR322 DNA methyl...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Wang, R Y, Zhang, X Y, Ehrlich, M
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1986
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC339531/
https://ncbi.nlm.nih.gov/pubmed/3005977
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