A human DNA-binding protein is methylation-specific and sequence-specific.

A nuclear protein isolated from human placenta, methylated DNA-binding protein (MDBP), binds selectively to DNA enriched in 5-methylcytosine. We now demonstrate that MDBP is a sequence-specific, as well as methylation-specific, DNA-binding protein. From ten restriction fragments of pBR322 DNA methyl...

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Detalles Bibliográficos

Publicado en:	Nucleic Acids Res
Principais autores:	Wang, R Y, Zhang, X Y, Ehrlich, M
Formato:	Artigo
Idioma:	Inglês
Publicado:	Oxford University Press 1986
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC339531/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3005977/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/14.4.1599
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