A human DNA-binding protein is methylation-specific and sequence-specific.
A nuclear protein isolated from human placenta, methylated DNA-binding protein (MDBP), binds selectively to DNA enriched in 5-methylcytosine. We now demonstrate that MDBP is a sequence-specific, as well as methylation-specific, DNA-binding protein. From ten restriction fragments of pBR322 DNA methyl...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
1986
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| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC339531/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3005977/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/14.4.1599 |
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