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Inhibition of follicular T helper cells by CD8(+) Treg is essential for self tolerance
The ability to produce vigorous immune responses that spare self tissues and organs depends on elimination of autoreactive T and B cells. However, purging of immature and mature self-reactive T and B cells is incomplete and may require additional censorship by cells programmed to suppress immune res...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3395240/ https://ncbi.nlm.nih.gov/pubmed/20844537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09370 |
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