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Amelioration of arthritis through mobilization of peptide-specific CD8(+) regulatory T cells

Current therapies to treat autoimmune disease focus mainly on downstream targets of autoimmune responses, including effector cells and cytokines. A potentially more effective approach would entail targeting autoreactive T cells that initiate the disease cascade and break self tolerance. The murine M...

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Autors principals: Leavenworth, Jianmei W., Tang, Xiaolei, Kim, Hye-Jung, Wang, Xiaoyang, Cantor, Harvey
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582146/
https://ncbi.nlm.nih.gov/pubmed/23376792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66938
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