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A p85α–osteopontin axis couples the ICOS receptor to sustained Bcl-6 expression by follicular helper and regulatory T cells
Follicular helper T (T(FH)) cells and follicular regulatory T (T(FR)) cells regulate the quantity and quality of humoral immunity. Although both cell types highly express the co-stimulatory receptor ICOS and require the transcription factor Bcl-6 for their differentiation, the ICOS-dependent pathway...
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| Yayımlandı: | Nat Immunol |
|---|---|
| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4405167/ https://ncbi.nlm.nih.gov/pubmed/25436971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3050 |
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