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The Impact of Macrophage Nucleotide Pools on HIV-1 Reverse Transcription, Viral Replication, and the Development of Novel Antiviral Agents

Macrophages are ubiquitous and represent a significant viral reservoir for HIV-1. Macrophages are nondividing, terminally differentiated cells, which have a unique cellular microenvironment relative to actively dividing T lymphocytes, all of which can impact HIV-1 infection/replication, design of in...

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Detalhes bibliográficos
Main Authors: Gavegnano, Christina, Kennedy, Edward M., Kim, Baek, Schinazi, Raymond F.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395185/
https://ncbi.nlm.nih.gov/pubmed/22811909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/625983
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