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Base substitution mutations induced in the cI gene of lambda phage by neocarzinostatin chromophore: correlation with depyrimidination hotspots at the sequence AGC.

Treatment of intact lambda phage with the nonprotein chromophore of neocarzinostatin resulted in efficient phage inactivation and generation of clear-plaque mutants. Both effects required a preincubation at low pH to allow diffusion of chromophore into the phage head. Chromophore activation was then...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Povirk, L F, Goldberg, I H
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1986
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC339514/
https://ncbi.nlm.nih.gov/pubmed/2937016
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