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Neocarzinostatin chromophore-DNA adducts: evidence for a covalent linkage to the oxidized C-5' of deoxyribose.

The nonprotein chromophore of neocarzinostatin forms a variety of adducts with DNA. The predominant adduct recovered from nuclease digests of chromophore-treated poly(dA-dT). poly(dA-dT) is a compound with structure chromophore-d(TpApT). Mild acid hydrolysis of this compound released free adenine, w...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Povirk, L F, Goldberg, I H
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1982
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC326915/
https://ncbi.nlm.nih.gov/pubmed/6217447
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