ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium

The telomeric amplicon at 8p12 is common in oestrogen receptor-positive (ER+) breast cancers. Array-CGH and expression analyses of 1172 primary breast tumours revealed that ZNF703 was the single gene within the minimal amplicon and was amplified predominantly in the Luminal B subtype. Amplification...

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Détails bibliographiques
Auteurs principaux: Holland, Daniel G, Burleigh, Angela, Git, Anna, Goldgraben, Mae A, Perez-Mancera, Pedro A, Chin, Suet-Feung, Hurtado, Antonio, Bruna, Alejandra, Ali, H Raza, Greenwood, Wendy, Dunning, Mark J, Samarajiwa, Shamith, Menon, Suraj, Rueda, Oscar M, Lynch, Andy G, McKinney, Steven, Ellis, Ian O, Eaves, Connie J, Carroll, Jason S, Curtis, Christina, Aparicio, Samuel, Caldas, Carlos
Format: Artigo
Langue:Inglês
Publié: WILEY-VCH Verlag 2011
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395113/
https://ncbi.nlm.nih.gov/pubmed/21337521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201100122
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