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Who is in the driver's seat in 8p12 amplifications? ZNF703 in luminal B breast tumors
Two recent reports identify ZNF703 as an oncogene driving selection of frequent chromosome 8p12 amplifications in luminal B breast tumors. The estrogen-responsive ZNF703 gene encodes a transcriptional cofactor that, when overexpressed, induces cell proliferation and interferes with transforming grow...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3218931/ https://ncbi.nlm.nih.gov/pubmed/21635707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2873 |
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