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Notch and Mef2 synergize to promote proliferation and metastasis through JNK signal activation in Drosophila

Genetic analyses in Drosophila revealed a synergy between Notch and the pleiotropic transcription factor Mef2 (myocyte enhancer factor 2), which profoundly influences proliferation and metastasis. We show that these hyperproliferative and invasive Drosophila phenotypes are attributed to upregulation...

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Bibliografski detalji
Glavni autori: Pallavi, S K, Ho, Diana M, Hicks, Chindo, Miele, Lucio, Artavanis-Tsakonas, Spyros
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395089/
https://ncbi.nlm.nih.gov/pubmed/22580825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.129
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