Llwytho...

Notch and Mef2 synergize to promote proliferation and metastasis through JNK signal activation in Drosophila

Genetic analyses in Drosophila revealed a synergy between Notch and the pleiotropic transcription factor Mef2 (myocyte enhancer factor 2), which profoundly influences proliferation and metastasis. We show that these hyperproliferative and invasive Drosophila phenotypes are attributed to upregulation...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pallavi, S K, Ho, Diana M, Hicks, Chindo, Miele, Lucio, Artavanis-Tsakonas, Spyros
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395089/
https://ncbi.nlm.nih.gov/pubmed/22580825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.129
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