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Sequence dependence for bypass of thymine glycols in DNA by DNA polymerase I.

Single-stranded phage DNAs containing thymine glycols were prepared by oxidation with osmium tetroxide (OsO4) and were used as templates for DNA synthesis by E. coli DNA polymerase I. The induction of thymine glycol lesions in DNA, as measured by immunoassay, quantitatively accounted for an inhibiti...

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Autors principals: Hayes, R C, LeClerc, J E
Format: Artigo
Idioma:Inglês
Publicat: 1986
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC339482/
https://ncbi.nlm.nih.gov/pubmed/3945552
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