Early interleukin 6 production by leukocytes during ischemic acute kidney injury is regulated by TLR4

Although leukocytes infiltrate the kidney during ischemic acute kidney injury (AKI) and release interleukin 6 (IL6), their mechanism of activation is unknown. Here, we tested whether Toll-like receptor 4 (TLR4) on leukocytes mediated this activation by interacting with high-mobility group protein B1...

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Detalhes bibliográficos
Main Authors: Chen, Jianlin, Hartono, John R., John, Reji, Bennett, Michael, Zhou, Xin Jin, Wang, Yanxia, Wu, Qingqing, Winterberg, Pamela D., Nagami, Glenn T., Lu, Christopher Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394593/
https://ncbi.nlm.nih.gov/pubmed/21633411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2011.140
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