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Cell-to-cell variability in PI3K protein level regulates PI3K-AKT pathway activity in cell populations
BACKGROUND: Cell-to-cell variability in populations has been widely observed in mammalian cells. This heterogeneity can result from random stochastic events or can be deliberately maintained through regulatory processes. In the latter case, heterogeneity should confer a selective advantage that bene...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3394538/ https://ncbi.nlm.nih.gov/pubmed/21256021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.12.047 |
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