(124)I-huA33 Antibody Uptake Is Driven by A33 Antigen Concentration in Tissues from Colorectal Cancer Patients Imaged by Immuno-PET

The primary aim of this analysis was to examine the quantitative features of antibody–antigen interactions in tumors and normal tissue after parenteral administration of antitumor antibodies to human patients. METHODS: Humanized anti-A33 antibody (10 mg) labeled with the positron-emitting radionucli...

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Main Authors: O’Donoghue, Joseph A., Smith-Jones, Peter M., Humm, John L., Ruan, Shutian, Pryma, Daniel A., Jungbluth, Achim A., Divgi, Chaitanya R., Carrasquillo, Jorge A., Pandit-Taskar, Neeta, Fong, Yuman, Strong, Vivian E., Kemeny, Nancy E., Old, Lloyd J., Larson, Steven M.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394180/
https://ncbi.nlm.nih.gov/pubmed/22068895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.111.095596
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