(124)I-huA33 Antibody PET of Colorectal Cancer

Humanized A33 (huA33) is a promising monoclonal antibody that recognizes A33 antigen, which is present in more than 95% of colorectal cancers and in normal bowel. In this study, we took advantage of quantitative PET to evaluate (124)I huA33 targeting, biodistribution, and safety in patients with col...

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Hauptverfasser: Carrasquillo, Jorge A., Pandit-Taskar, Neeta, O’Donoghue, Joseph A., Humm, John L., Zanzonico, Pat, Smith-Jones, Peter M., Divgi, Chaitanya R., Pryma, Daniel A., Ruan, Shutian, Kemeny, Nancy E., Fong, Yuman, Wong, Douglas, Jaggi, Jaspreet S., Scheinberg, David A., Gonen, Mithat, Panageas, Katherine S., Ritter, Gerd, Jungbluth, Achim A., Old, Lloyd J., Larson, Steven M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394182/
https://ncbi.nlm.nih.gov/pubmed/21764796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.110.086165
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