Retooling a Blood-based Biomarker: Phase I Assessment of the High-Affinity CA19-9 Antibody HuMab-5B1 for Immuno-PET Imaging of Pancreatic Cancer

PURPOSE: In cancer patients with an abnormal biomarker finding, the source of the biomarker in the bloodstream must be located for confirmation of diagnosis, staging, and therapy planning. We evaluated if immuno-PET with the radiolabeled high-affinity antibody HuMab-5B1 (MVT-2163), binding to the ca...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Lohrmann, Christian, O’Reilly, Eileen M., O’Donoghue, Joseph, Pandit-Taskar, Neeta, Carrasquillo, Jorge A., Lyashchenko, Serge K., Ruan, Shutian, Teng, Rebecca, Scholz, Wolfgang, Maffuid, Paul W., Lewis, Jason S., Weber, Wolfgang A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052809/
https://ncbi.nlm.nih.gov/pubmed/31540979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-3667
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