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Effective correction of experimental errors in quantitative proteomics using stable isotope labeling by amino acids in cell culture (SILAC)

Accurate and reliable quantitative proteomics in cell culture has been considerably facilitated by the introduction of the stable isotope labeling by amino acids in cell culture (SILAC), combined with high resolution mass spectrometry. There are however several major sources of quantification errors...

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Bibliographic Details
Main Authors: Park, Sung-Soo, Wu, Wells W., Zhou, Yu, Shen, Rong-Fong, Martin, Bronwen, Maudsley, Stuart
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394155/
https://ncbi.nlm.nih.gov/pubmed/22575385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2012.04.035
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