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Effective correction of experimental errors in quantitative proteomics using stable isotope labeling by amino acids in cell culture (SILAC)

Accurate and reliable quantitative proteomics in cell culture has been considerably facilitated by the introduction of the stable isotope labeling by amino acids in cell culture (SILAC), combined with high resolution mass spectrometry. There are however several major sources of quantification errors...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Park, Sung-Soo, Wu, Wells W., Zhou, Yu, Shen, Rong-Fong, Martin, Bronwen, Maudsley, Stuart
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394155/
https://ncbi.nlm.nih.gov/pubmed/22575385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2012.04.035
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