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Aptamer That Binds to the gD Protein of Herpes Simplex Virus 1 and Efficiently Inhibits Viral Entry

The ectodomain of the gD protein of herpes simplex viruses (HSVs) plays an important role in viral entry by binding to specific cellular coreceptors and mediating viral entry to the host cells. In the present study, we isolated RNA aptamers (aptamer-1 and aptamer-5) that specifically bind to the gD...

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Autori principali: Gopinath, Subash C. B., Hayashi, Kyoko, Kumar, Penmetcha K. R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393590/
https://ncbi.nlm.nih.gov/pubmed/22514343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00377-12
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