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Glycoprotein B of Herpes Simplex Virus 2 Has More than One Intracellular Conformation and Is Altered by Low pH

The crystal structure of herpes simplex virus (HSV) gB identifies it as a class III fusion protein, and comparison with other such proteins suggests this is the postfusion rather than prefusion conformation, although this is not proven. Other class III proteins undergo a pH-dependent switch between...

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Detalhes bibliográficos
Autor principal: Muggeridge, Martin I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393537/
https://ncbi.nlm.nih.gov/pubmed/22514344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06668-11
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