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Murine Cytomegalovirus Targets Transcription Factor ATF4 To Exploit the Unfolded-Protein Response
The unfolded-protein response (UPR), activated by sensor molecules PERK, ATF6, and IRE1 to resolve endoplasmic reticulum (ER) stress, has emerged as a key target for host cells and viruses to control the infection outcomes. The UPR regulates ER protein folding, controls cell fate upon ER stress, and...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3393534/ https://ncbi.nlm.nih.gov/pubmed/22496230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00200-12 |
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