Rifapentine Is Not More Active than Rifampin against Chronic Tuberculosis in Guinea Pigs

Rifamycins are key sterilizing drugs in the current treatment of active tuberculosis (TB). Daily dosing of rifapentine (P), a potent rifamycin with high intracellular accumulation, in place of rifampin (R) in the standard antitubercular regimen significantly shortens the duration of treatment needed...

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Détails bibliographiques
Auteurs principaux: Dutta, Noton K., Illei, Peter B., Peloquin, Charles A., Pinn, Michael L., Mdluli, Khisimuzi E., Nuermberger, Eric L., Grosset, Jacques H., Karakousis, Petros C.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2012
Sujets:
Experimental Therapeutics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393407/
https://ncbi.nlm.nih.gov/pubmed/22547623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00500-12
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