Optimal Dosing of Miltefosine in Children and Adults with Visceral Leishmaniasis

Only anecdotal data are available on the pharmacokinetics (PK) of miltefosine in children suffering from visceral leishmaniasis (VL). While failure rates were higher in children with VL, steady-state concentrations appeared lower than those seen with adults. We hypothesized that the current linear d...

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Bibliographic Details
Main Authors: Dorlo, Thomas P. C., Huitema, Alwin D. R., Beijnen, Jos H., de Vries, Peter J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393397/
https://ncbi.nlm.nih.gov/pubmed/22585212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00292-12
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