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Optimal Dosing of Miltefosine in Children and Adults with Visceral Leishmaniasis

Only anecdotal data are available on the pharmacokinetics (PK) of miltefosine in children suffering from visceral leishmaniasis (VL). While failure rates were higher in children with VL, steady-state concentrations appeared lower than those seen with adults. We hypothesized that the current linear d...

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Detalhes bibliográficos
Main Authors: Dorlo, Thomas P. C., Huitema, Alwin D. R., Beijnen, Jos H., de Vries, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393397/
https://ncbi.nlm.nih.gov/pubmed/22585212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00292-12
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