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Translating DRiPs: progress in understanding viral and cellular sources of MHC class I peptide ligands

It has been 15 years since we proposed the defective ribosomal product (DRiP) hypothesis to explain the rapid presentation of viral peptides by MHC class I molecules on the surface of infected cells. Here, we review the evidence for the contribution of DRiPs to antigen processing, pointing to the un...

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Bibliographic Details
Main Authors: Dolan, Brian P., Bennink, Jack R., Yewdell, Jonathan W.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393103/
https://ncbi.nlm.nih.gov/pubmed/21416150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-011-0656-z
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