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Translating DRiPs: MHC class I immunosurveillance of pathogens and tumors

MHC class I molecules display oligopeptides on the cell surface to enable T cell immunosurveillance of intracellular pathogens and tumors. Speed is of the essence in detecting viruses, which can complete a full replication cycle in just hours, whereas tumor detection is typically a finding-the-needl...

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Autors principals: Antón, Luis C., Yewdell, Jonathan W.
Format: Artigo
Idioma:Inglês
Publicat: Society for Leukocyte Biology 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958739/
https://ncbi.nlm.nih.gov/pubmed/24532645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1113599
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