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MHC class I antigen processing distinguishes endogenous antigens based on their translation from cellular vs. viral mRNA
To better understand the generation of MHC class I-associated peptides, we used a model antigenic protein whose proteasome-mediated degradation is rapidly and reversibly controlled by Shield-1, a cell-permeant drug. When expressed from a stably transfected gene, the efficiency of antigen presentatio...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3344963/ https://ncbi.nlm.nih.gov/pubmed/22509014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1112387109 |
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