Endogenous viral antigen processing generates peptide-specific MHC class I cell-surface clusters

Sensitivity is essential in CD8+ T-cell killing of virus-infected cells and tumor cells. Although the affinity of the T-cell receptor (TCR) for antigen is relatively low, the avidity of T cell-antigen–presenting cell interactions is greatly enhanced by increasing the valence of the interaction. It i...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Lu, Xiuju, Gibbs, James S., Hickman, Heather D., David, Alexandre, Dolan, Brian P., Jin, Yetao, Kranz, David M., Bennink, Jack R., Yewdell, Jonathan W., Varma, Rajat
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2012
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458372/
https://ncbi.nlm.nih.gov/pubmed/22949678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208696109
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items