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Endogenous viral antigen processing generates peptide-specific MHC class I cell-surface clusters
Sensitivity is essential in CD8+ T-cell killing of virus-infected cells and tumor cells. Although the affinity of the T-cell receptor (TCR) for antigen is relatively low, the avidity of T cell-antigen–presenting cell interactions is greatly enhanced by increasing the valence of the interaction. It i...
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| Hlavní autoři: | , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3458372/ https://ncbi.nlm.nih.gov/pubmed/22949678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208696109 |
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