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Allostery and cooperativity in Escherichia coli Aspartate Transcarbamoylase

The allosteric enzyme aspartate transcarbamoylase (ATCase) from Escherichia coli has been the subject of investigations for approximately 50 years. This enzyme controls the rate of pyrimidine nucleotide biosynthesis by feedback inhibition, and helps to balance the pyrimidine and purine pools by comp...

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Détails bibliographiques
Auteur principal: Kantrowitz, Evan R.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393099/
https://ncbi.nlm.nih.gov/pubmed/22198283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2011.10.024
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