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Structural Model of the R State of Escherichia coli Aspartate Transcarbamoylase with Substrates Bound

The allosteric enzyme aspartate transcarbamoylase (ATCase) exists in two conformational states. The enzyme, in the absence of substrates is primarily in the low-activity T state, is converted to the high-activity R state upon substrate binding, and remains in the R state until substrates are exhaust...

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Hlavní autoři: Wang, Jie, Eldo, Joby, Kantrowitz, Evan R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720131/
https://ncbi.nlm.nih.gov/pubmed/17603076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.06.011
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