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Structural Model of the R State of Escherichia coli Aspartate Transcarbamoylase with Substrates Bound

The allosteric enzyme aspartate transcarbamoylase (ATCase) exists in two conformational states. The enzyme, in the absence of substrates is primarily in the low-activity T state, is converted to the high-activity R state upon substrate binding, and remains in the R state until substrates are exhaust...

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Main Authors: Wang, Jie, Eldo, Joby, Kantrowitz, Evan R.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720131/
https://ncbi.nlm.nih.gov/pubmed/17603076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.06.011
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