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Cardiac Overexpression of Metallothionein Rescues Cold Exposure-Induced Myocardial Contractile Dysfunction through Attenuation of Cardiac Fibrosis Despite Cardiomyocyte Mechanical Anomalies

Cold exposure is associated with an increased prevalence for cardiovascular disease although the mechanism is unknown. Metallothionein, a heavy metal scavenging antioxidant, protects against cardiac anomalies. This study was designed to examine the impact of metallothionein on cold exposure-induced...

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Библиографические подробности
Главные авторы: Zhang, Yingmei, Hu, Nan, Hua, Yinan, Richmond, Kacy L., Dong, Feng, Ren, Jun
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392511/
https://ncbi.nlm.nih.gov/pubmed/22565031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2012.04.005
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