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Cardiac-Specific Overexpression of Metallothionein Rescues Nicotine-Induced Cardiac Contractile Dysfunction and Interstitial Fibrosis
Cigarette smoking is a devastating risk factor for cardiovascular diseases and nicotine is believed the main toxin component responsible for the toxic myocardial effects of smoking. Nonetheless, neither the precise mechanism of nicotine -induced cardiac dysfunction nor effective treatment is elucida...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3061624/ https://ncbi.nlm.nih.gov/pubmed/21238558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2011.01.007 |
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