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Improving cardiac conduction with a skeletal muscle sodium channel by gene and cell therapy
The voltage-gated Na(+) channel is a critical determinant of the action potential upstroke. Increasing Na(+) conductance may speed action potential propagation. Here we propose use of the skeletal muscle Na(+) channel SkM1 as a more favorable gene than the cardiac isoform SCN5A to enhance conduction...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3392452/ https://ncbi.nlm.nih.gov/pubmed/22526298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0b013e3182588b00 |
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