NK1.1(+) cells and IL-22 regulate vaccine-induced protective immunity against challenge with Mycobacterium tuberculosis

We previously found that human NK cells lyse M. tuberculosis (M. tb)-infected monocytes and alveolar macrophages, and upregulate CD8(+) T-cell responses. We also found that human NK cells produce IL-22, which inhibits intracellular growth of M. tb, and that NK cells lyse M. tb-expanded CD4(+)CD25(+)...

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Main Authors: Dhiman, Rohan, Periasamy, Sivakumar, Barnes, Peter F., Jaiswal, Ankita Garg, Paidipally, Padmaja, Barnes, Amanda B., Tvinnereim, Amy, Vankayalapati, Ramakrishna
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392427/
https://ncbi.nlm.nih.gov/pubmed/22711885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102833
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