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NK1.1(+) cells and IL-22 regulate vaccine-induced protective immunity against challenge with Mycobacterium tuberculosis
We previously found that human NK cells lyse M. tuberculosis (M. tb)-infected monocytes and alveolar macrophages, and upregulate CD8(+) T-cell responses. We also found that human NK cells produce IL-22, which inhibits intracellular growth of M. tb, and that NK cells lyse M. tb-expanded CD4(+)CD25(+)...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3392427/ https://ncbi.nlm.nih.gov/pubmed/22711885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102833 |
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