Phosphorylated STAT3 and PD-1 regulate IL-17 production and IL-23 receptor expression in Mycobacterium tuberculosis infection

We studied the factors that regulate IL-23 receptor expression and IL-17 production in human tuberculosis infection. Mycobacterium tuberculosis (M. tb)-stimulated CD4+ cells from tuberculosis patients secreted less IL-17 than did CD4+ cells from healthy tuberculin reactors (PPD+). M. tb cultured mon...

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Autori principali: Bandaru, Anuradha, Devalraju, Kamakshi P, Paidipally, Padmaja, Dhiman, Rohan, Venkatasubramanian, Sambasivan, Barnes, Peter F, Vankayalapati, Ramakrishna, Valluri, Vijayalakshmi
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106993/
https://ncbi.nlm.nih.gov/pubmed/24643836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201343680
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