Toso, a functional IgM receptor, is regulated by IL-2 in T and NK cells()

We find that the cell surface receptor Toso is dramatically down-regulated by in vitro stimulation of human T and NK cells with IL-2 in a STAT5 dependent manner. The fact that IL-2 is known to prime NK and T cells for Fas/TNF-mediated activation induced cell death (AICD) fits nicely with the origina...

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Bibliografiske detaljer
Main Authors: Murakami, Yousuke, Narayanan, Sriram, Su, Su, Childs, Richard, Krzewski, Konrad, Borrego, Francisco, Weck, Jennifer, Coligan, John E.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392415/
https://ncbi.nlm.nih.gov/pubmed/22675200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200840
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