Bladder Cancer Diagnosis and Identification of Clinically Significant Disease by Combined Urinary Detection of Mcm5 and Nuclear Matrix Protein 22

BACKGROUND: Urinary biomarkers for bladder cancer detection are constrained by inadequate sensitivity or specificity. Here we evaluate the diagnostic accuracy of Mcm5, a novel cell cycle biomarker of aberrant growth, alone and in combination with NMP22. METHODS: 1677 consecutive patients under inves...

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Auteurs principaux: Kelly, John D., Dudderidge, Tim J., Wollenschlaeger, Alex, Okoturo, Odu, Burling, Keith, Tulloch, Fiona, Halsall, Ian, Prevost, Teresa, Prevost, Andrew Toby, Vasconcelos, Joana C., Robson, Wendy, Leung, Hing Y., Vasdev, Nikhil, Pickard, Robert S., Williams, Gareth H., Stoeber, Kai
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
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Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392249/
https://ncbi.nlm.nih.gov/pubmed/22792272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040305
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