Bladder Cancer Diagnosis and Identification of Clinically Significant Disease by Combined Urinary Detection of Mcm5 and Nuclear Matrix Protein 22

BACKGROUND: Urinary biomarkers for bladder cancer detection are constrained by inadequate sensitivity or specificity. Here we evaluate the diagnostic accuracy of Mcm5, a novel cell cycle biomarker of aberrant growth, alone and in combination with NMP22. METHODS: 1677 consecutive patients under inves...

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Main Authors: Kelly, John D., Dudderidge, Tim J., Wollenschlaeger, Alex, Okoturo, Odu, Burling, Keith, Tulloch, Fiona, Halsall, Ian, Prevost, Teresa, Prevost, Andrew Toby, Vasconcelos, Joana C., Robson, Wendy, Leung, Hing Y., Vasdev, Nikhil, Pickard, Robert S., Williams, Gareth H., Stoeber, Kai
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392249/
https://ncbi.nlm.nih.gov/pubmed/22792272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040305
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