Bladder Cancer Diagnosis and Identification of Clinically Significant Disease by Combined Urinary Detection of Mcm5 and Nuclear Matrix Protein 22

BACKGROUND: Urinary biomarkers for bladder cancer detection are constrained by inadequate sensitivity or specificity. Here we evaluate the diagnostic accuracy of Mcm5, a novel cell cycle biomarker of aberrant growth, alone and in combination with NMP22. METHODS: 1677 consecutive patients under inves...

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Bibliografiska uppgifter
Huvudupphovsmän: Kelly, John D., Dudderidge, Tim J., Wollenschlaeger, Alex, Okoturo, Odu, Burling, Keith, Tulloch, Fiona, Halsall, Ian, Prevost, Teresa, Prevost, Andrew Toby, Vasconcelos, Joana C., Robson, Wendy, Leung, Hing Y., Vasdev, Nikhil, Pickard, Robert S., Williams, Gareth H., Stoeber, Kai
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2012
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392249/
https://ncbi.nlm.nih.gov/pubmed/22792272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040305
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