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Signaling Circuitries Controlling Stem Cell Fate: To Be or Not To Be

The integration of extrinsic and intrinsic signals is required to preserve the self-renewal and tissue regenerative capacity of adult stem cells, while protecting them from malignant conversion or loss of proliferative potential by death, differentiation or senescence. Here we review emerging signal...

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Main Authors: Iglesias-Bartolome, Ramiro, Gutkind, J. Silvio
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391582/
https://ncbi.nlm.nih.gov/pubmed/21880478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2011.08.002
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