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Towards an Enantioselective Synthesis of (−)-Zampanolide: Preparation of the C9-C20 Region
[Image: see text] Progress towards the synthesis of the microtubule-stabilizing agent, (−)-zampanolide, is reported. Construction of the 2,6-cis-tetrahydropyran ring was accomplished utilizing ether transfer methodology in conjunction with an intramolecular radical cyclization reaction. Efficient in...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3391338/ https://ncbi.nlm.nih.gov/pubmed/22720980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol301383a |
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