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Towards an Enantioselective Synthesis of (−)-Zampanolide: Preparation of the C9-C20 Region

[Image: see text] Progress towards the synthesis of the microtubule-stabilizing agent, (−)-zampanolide, is reported. Construction of the 2,6-cis-tetrahydropyran ring was accomplished utilizing ether transfer methodology in conjunction with an intramolecular radical cyclization reaction. Efficient in...

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Detalhes bibliográficos
Main Authors: Wilson, Matthew R., Taylor, Richard E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391338/
https://ncbi.nlm.nih.gov/pubmed/22720980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol301383a
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