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DNA replication fidelity in Escherichia coli: a multi-DNA polymerase affair

High accuracy (fidelity) of DNA replication is important for cells to preserve genetic identity and to prevent accumulation of deleterious mutations. The error rate during DNA replication is as low as 10(−9) to 10(−11) errors per base pair. How this low level is achieved is an issue of major interes...

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Bibliographic Details
Main Authors: Fijalkowska, Iwona J., Schaaper, Roel M., Jonczyk, Piotr
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391330/
https://ncbi.nlm.nih.gov/pubmed/22404288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1574-6976.2012.00338.x
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