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DNA replication fidelity in Escherichia coli: a multi-DNA polymerase affair

High accuracy (fidelity) of DNA replication is important for cells to preserve genetic identity and to prevent accumulation of deleterious mutations. The error rate during DNA replication is as low as 10(−9) to 10(−11) errors per base pair. How this low level is achieved is an issue of major interes...

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Detalhes bibliográficos
Main Authors: Fijalkowska, Iwona J., Schaaper, Roel M., Jonczyk, Piotr
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391330/
https://ncbi.nlm.nih.gov/pubmed/22404288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1574-6976.2012.00338.x
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