DISCOVERY OF NOVEL GLUCOSE-REGULATED PROTEINS IN ISOLATED HUMAN PANCREATIC ISLETS USING LC-MS/MS-BASED PROTEOMICS

The prevalence of diabetes mellitus is increasing dramatically throughout the world, and the disease has become a major public health issue. The most common form of the disease, type 2 diabetes, is characterized by insulin resistance and insufficient insulin production from the pancreatic beta-cell....

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Main Authors: Schrimpe-Rutledge, Alexandra C., Fontès, Ghislaine, Gritsenko, Marina A., Norbeck, Angela D., Anderson, David J., Waters, Katrina M., Adkins, Joshua N., Smith, Richard D., Poitout, Vincent, Metz, Thomas O.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391329/
https://ncbi.nlm.nih.gov/pubmed/22578083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr3002996
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